Other medicines—Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking growth hormone, it is especially important that your health care professional know if you are taking any of the following:

Corticosteroids (cortisone-like medicines)—These medicines can interfere with the effects of growth hormone

The dose of these medicines will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so. For somatrem

For injection dosage form: For treatment of growth failure caused by growth hormone deficiency: Children—Dose is based on body weight and must be determined by your doctor. The usual total weekly dose is 0.3 milligram (mg) per kilogram (kg) (0.136 mg per pound) of body weight. This is divided into smaller doses and usually is injected under the skin, but may be injected into a muscle as determined by your doctor.

For somatropin

For injection dosage form: For treatment of growth failure caused by growth hormone deficiency: Adults—Dose is based on body weight and must be determined by your doctor. At first, it is usually 0.006 milligram (mg) per kilogram (kg) (0.0027 mg per pound) of body weight injected under the skin once a day. Your doctor may then increase the dose if needed. Children—Dose is based on body weight and must be determined by your doctor. The usual total weekly dose is 0.16 to 0.3 mg per kg (0.073 to 0.136 mg per pound) of body weight. This is divided into smaller doses and usually is injected under the skin, but may be injected into a muscle as determined by your doctor. Children using Norditropin Cartridges—Dose is based on body weight and must be determined by your doctor. The usual dose is 0.024 to 0.034 mg per kg (0.011 to 0.015 mg per pound of body weight) injected under the skin, on 6 to 7 days a week. The dose is given using a Nordipen™ injection device. For treatment of growth failure caused by kidney disease: Children—Dose is based on body weight and must be determined by your doctor. The usual total weekly dose is 0.35 mg per kg (0.16 mg per pound) of body weight. This is divided into smaller daily doses and is injected under the skin or into a muscle. For treatment of growth failure caused by Turner's syndrome: Children—Dose is based on body weight and must be determined by your doctor. The usual total weekly dose is 0.375 mg per kg (0.17 mg per pound) of body weight. This is divided into smaller doses and is injected under the skin. For treatment of growth failure caused by Prader-Willi syndrome: Children—Dose is based on body weight and must be determined by your doctor. The usual total weekly dose is 0.24 mg per kg (0.11 mg per pound) of body weight. This is divided into 6 or 7 smaller doses over the course of the week and is injected under the skin. For treatment of weight loss caused by acquired immunodeficiency disease (AIDS): Adults weighing more than 121 pounds (55 kg)—6 mg injected under the skin once a day at bedtime. Adults weighing 99 to 121 pounds (45 to 55 kg)—5 mg injected under the skin once a day at bedtime. Adults weighing 77 to 98 pounds (35 to 44 kg)—4 mg injected under the skin once a day at bedtime. Adults weighing less than 77 pounds (35 kg)—Dose is based on body weight and must be determined by your doctor. It is usually 0.1 mg per kg (0.045 mg per pound) of body weight injected under the skin once a day at bedtime. Children—Use and dose must be determined by your doctor.

Storage—

To store this medicine:

	Keep out of the reach of children.
	Store away from heat and direct light.
	Store at temperature directed by your health care professional or the manufacturer.
	Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.